Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche ''Togo Rosati''

Authors Petrini S, Curini V, Righi C, Cammà C, Di Lollo V, Tinelli E, Mincarelli L F, Rossi E, Costantino G, Secondini B, Pirani S, Giammarioli M, Feliziani F

Abstract Bovine alphaherpesvirus-1 (BoAHV-1) infection is common in cattle worldwide. However, information on the spread of BoAHV-1-circulating strains in Italy remains limited. In this study, we investigated an outbreak characterized by severe respiratory symptoms in a cattle herd (n = 30) located in Central Italy. BoAHV-1 was isolated from three cattle in a cell culture, which confirmed viral infection. Next, we characterized one (16453/07 TN) of the three isolates of BoAHV-1 using whole-genome sequencing. BLASTn and phylogenetic analysis revealed a nucleotide identity >99% with all BoAHV-1 strains belonging to subtype 1.1, highlighting the genetic stability of the virus. This study reports the first full genomic characterization of a BoAHV-1 isolate in Italy, enriching our understanding of the genetic characteristics of the circulating BoAHV-1 strain in Italy.

Publish Date 2024

Volume 16 (1)

ISSN 1999-4915

DOI doi.org/10.3390/v16010150

URL https://www.mdpi.com/1999-4915/16/1/150

Journal Viruses

Pages art. n. 150

PMID 38275960