Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche ''Togo Rosati''

Authors  Stecconi T, Tavoloni T, Stramenga A, Bacchiocchi S, Barola C, Dubbini A, Galarini R, Moretti S, Sagratini G, Piersanti A

Abstract  Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are synthetic, stable, fluorinated molecules widely used in consumer products. They are non-biodegradable, persistent and bio-accumulating. In 2020 European Food Safety Authority (EFSA) lowered the Tolerable Weekly Intake (TWI) for the four PFASs (PFOA, PFOS, PFNA, PFHxS) and in 2022, the EU issued a Recommendation asking to monitor twenty-one PFASs in food. Since 1st January 2023 limits in food were set. Here we report a sensitive, straightforward and robust procedure enabling the determination of 19 PFAS in food matrices using a liquid chromatography mass spectrometer (LC–MS/MS). Few are the published methods applicable to the different food matrices and covering the molecules listed in Recommendation 2022/1431, fulfilling the LOQs requested. The method was satisfactory validated (UNI CEI EN ISO/IEC 17025:2018 and Regulation (EU) 2022/1428) and used to investigate hen egg samples, highlighting home-produced eggs as the more critical egg farming process for PFAS accumulation.

Publish Date 2024

Volume 266 (2)

ISSN 1873-3573

DOI  doi.org/10.1016/j.talanta.2023.125054

URL https://www.sciencedirect.com/science/article/pii/S0039914023008056?via%3Dihub

Journal  Talanta

Pages art. n. 125054

PMID  37611367