Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche ''Togo Rosati''

Authors   Bianchini E, Mancini F, Di Meo A, Stabile A, Buratta S, Moscati L, Pistilli A, Floridi C, Pepe M, Chiaradia E

Abstract    Lidocaine (LD) is one of the most commonly used local anesthetics for performing arthroscopic surgery and managing of osteoarthritic pain in both human and veterinary medicine. However, over the last years, several studies have focused on the chondrotoxic effects of LD. In order to ensure that intra-articular lidocaine is safe to use, treatments aimed at mitigating chondrocyte death have recently been investigated. The aim of this study is to evaluate the possible protective effects of platelet-rich plasma (PRP) against LD cytotoxicity on canine articular chondrocytes.

Publish Date  2018

Volume    60 (1)

ISSN    1751-0147

DOI    doi.org/10.1186/s13028-018-0418-0

URL  https://actavetscand.biomedcentral.com/articles/10.1186/s13028-018-0418-0

Journal  Acta Veterinaria Scandinavica

Pages   63

PMID  30367652